99% Apixaban CAS 503612-47-3

Tsanangudzo Pfupi:

Kemikari zita:Apixaban
Rimwe zita:1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine -3-carboxaMide;1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,
5-dihydropyrazolo[3,4-c]pyridine-3-carboxaMide
Nhamba yeCAS:503612-47-3
Kuchena:99% min
Formula:C25H25N5O4
Molecular Weight:459.50
Chemical Properties:Apixaban ichena crystalline powder.Iyo imhando nyowani yemuromo Xa factor inhibitor, uye zita rayo rekutengesa ndiEliquis.Apixaban inoshandiswa kurapa varwere vakuru vari kusarudzwa hudyu kana kutsiva mabvi kuvhiyiwa kudzivirira venous thromboembolism (VTE).

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Product Detail

Product Tags

Tsanangudzo

ITEM	STANDARD
Chitarisiko	Kuchena kusvika kune-chena kusimba
Kuchena	≥ 99%

Application

Apixaban rudzi rutsva rweoral anticoagulant, rudzi rutsva rweoral factor Xa inhibitor, iyo inoshandiswa kudzivirira uye kubata ropa.
Apixaban itsva oral factor Xa inhibitor yakabatanidzwa neBristol-Myers Squibb uye Pfizer.Nekudzivisa yakakosha coagulation factor Xa, apixaban inodzivirira thrombin chizvarwa uye thrombosis.

Musi waKubvumbi 26, 2007, Bristol-Myers Squibb naPfizer vakazivisa kuvandudzwa kwakabatana kweiyo itsva oral anticoagulant apixaban iri yeBristol-Myers Squibb seimwe yakakwidziridzwa kune warfarin.
Muna Chivabvu 2011, apixaban ndiyo yaive yekutanga kubvumidzwa kudzivirira venous thrombosis muvarwere vakura vanovhiyiwa kusarudzwa kwehudyu kana kutsiva mabvi munyika dze27 EU, Iceland neNorway.
Musi waNovember 20, 2012, European Commission yakabvumira ELIQUIS (apixaban) yekudzivirira sitiroko uye systemic embolism kune vanhu vakuru vane non-valvular atrial fibrillation (NVAF) ine imwe kana yakawanda yengozi.
The Canadian Food and Drug Administration, Japan, uye US Food and Drug Administration yakazobvumira ELIQUIS (apixaban) yekudzivirira sitiroko uye systemic embolism kune vanhu vakuru vane non-valvular atrial fibrillation (NVAF) ine imwe kana yakawanda yengozi.
Musi waApril 12, 2013, ELIQUIS (Apixaban), yakaziviswa zviri pamutemo pamusika muChina.Apixaban inoveli oral factor Xa inhibitor yekudzivirira venous thromboembolism (VTE) muvarwere vakuru vari kusarudzwa hudyu kana kutsiva mabvi.Kutangwa kwayo kunopa yakachengeteka uye inoshanda sarudzo nyowani yeanticoagulation mushure mekuvhiyiwa kwemapfupa mukudzidzira kwekiriniki, uye inounza nhau dzakanaka kuvarwere veChinese vari kusarudzwa hudyu/mabvi kutsiva.
Zvidzidzo zvekiriniki zvakasimbisa kuti zvichienzaniswa ne40 mg subcutaneous jekiseni yeanoxaparin kamwe chete pazuva, 2.5 mg yeELIQUIS (Apixaban) nemuromo kaviri pazuva inoshanda zvakanyanya mukudzivirira venous thromboembolic zviitiko mushure mehudyu kana mabvi kutsiva kuvhiyiwa, uye haina kuwedzera njodzi ye kubuda ropa.